Sterilizing Grade PVDF0.2 Micron Membrane Filter Cartridge


SERENE PVDF pleated cartridge filters are uniquely constructed with polyvinylidene fluoride media. PVDF membranes offer broad chemical compatibility with low extractable levels, high protein binding and high chemical inertness. The pleat technology maximizes the useful surface area of the filter while maintaining proper flow paths between media pleats. These cartridge filters are manufactured with PVDF and polypropylene support media, both materials are chemically inert non-shedding and biologically safe according to FDA, USP and EEC requirements for pharmaceutical and food contact use. Thermoplastic sealing technologies are used in the cartridge construction eliminating the need for potentially contaminating adhesives.

The hydrophilic polyvinylidene fluoride (PVDF) membrane filter is available in discs, capsules, high capacity Mega capsule, and cartridges with 0.1 µm, 0.2 µm, 0.4 µm and 0.6 µm absolute ratings. It is optimized for the clarification, prefiltration and sterile filtration of liquids. Manufactured by a state-of-the-art process, the filter provides the highest flow rates of any PVDF filter.

Design Features

  • Modified PVDF membrane for inherent water wettability
  • Highest flow rates of any PVDF membrane filter
  • Extremely low protein and preservative binding
  • Compatible with a wide range of solvents, acids and chemicals
  • Extremely low extractables
  • Repeatedly steam sterilizable in situ
  • Meets ASTM bacterial validation standards
  • Cleanroom manufactured

Application

  • Sterile filtration of parenterals, antibiotics, vaccines, diagnostics, buffers, diluents, reagents, serum, tissue culture media and media additives
  • Clarification and purification of deionized water, aqueous solvents, acids, bases and plating solutions
  • Clarification and stabilization of beer, wine and bottled water products
  • Particulate removal and bioburden reduction in aqueous liquid streams

Specifications

Materials of Construction

  • Membrane: Hydrophilic Polyvinylidene Fluoride (PVDF
  • Membrane Supports: Polypropylene
  • Cage, Core, End Caps: Polypropylene
  • O-Rings: Silicone, EPDM, Viton, Buna etc

Dimensions

  • Diameter Φ68
  • Length 5 inch, 10 inch, 20 inch, 30 inch,40 inch

Operating Conditions

Maximum Forward Differential Pressure:

  • 3.7 bar @ 21°C
  • 2.1 bar @ 80°C

Filtration Area, ft²

  • 7.5 ft² per 10-inch cartridge

Bacterial Retention

  • Passed bacterial challenge testing using of Brevundimonas diminuta (ATCC19146) in accordance with the current HIMA challenge methodology (ASTM F838-83) at a minimum challenge concentration of 1 x 107.
  • Validation Guide available upon request.

Bio-Safety

  • Filter effluent is non-pyrogenic per USP bacterial endotoxin (<0.25 EU/ml)

Sterilization & Autoclaving

Sterilized by autoclaving for up to 30 cycles at 123 °C (257 °F) for 30 minutes. The filters can also be sterilized by steam-in-place procedure up to 30 cycles at 135 °C (275 °F) for 30 minutes .The filters can also sanitized by hot water or common chemicals that are compatible with filter components.